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NYC Cancer Trial Delivers ‘Unheard-of’ Result: Complete Remission for Everyone

Patients with a particular kind of cancer and a particular kind of mutation received a new therapy called dostarlimab and had results not seen in a cancer trial before


According to the NEJM paper and the Times report, all 12 patients had rectal cancer that had not spread beyond the local area, and their tumors all exhibited a mutation affecting the ability of cells to repair damage to DNA.

After being treated with the drug, dostarlimab, all 12 are now in complete remission, with no surgery or chemotherapy, no severe side effects — and no trace of cancer whatsoever anywhere in their body.


Doctors quoted by the Times said that while the results were promising, they would need to be replicated and expanded – nor was it clear if the medication in question would be useful beyond this specific application.

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